Mapping of c-Fos expression in the rat brain during the evolution of pentylenetetrazol-kindled seizures
J Szyndler, P Maciejak, D Turzyńska, A Sobolewska… - Epilepsy & behavior, 2009 - Elsevier
c-Fos protein immunocytochemistry was used to map the brain structures recruited during
the evolution of seizures that follows repeated administration of a subconvulsive dose
(35mg/kg, ip) of pentylenetetrazol in rats. c-Fos appeared earliest in nucleus accumbens
shell, piriform cortex, prefrontal cortex, and striatum (stages 1 and 2 of kindling in
comparison to control, saline-treated animals). At the third stage of kindling, central
amygdala nuclei, entorhinal cortex, and lateral septal nuclei had enhanced concentrations …
the evolution of seizures that follows repeated administration of a subconvulsive dose
(35mg/kg, ip) of pentylenetetrazol in rats. c-Fos appeared earliest in nucleus accumbens
shell, piriform cortex, prefrontal cortex, and striatum (stages 1 and 2 of kindling in
comparison to control, saline-treated animals). At the third stage of kindling, central
amygdala nuclei, entorhinal cortex, and lateral septal nuclei had enhanced concentrations …