The long-term effects of infantile seizures on the development of seizures in adulthood were
studied in rats. Infantile seizures of varying severity were induced with intraperitoneal
injections of kainic acid in 15-day-old rats. In adulthood the seizure susceptibility of the rats
was determined by kindling the left amygdala and by measuring their ability to resist
recurrent seizures. The results suggest that infantile status epilepticus is associated with a
very high mortality; however in the surviving rats, infantile seizures even as severe as status …