Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity
SD Norrholm, T Jovanovic, IW Olin, LA Sands… - Biological …, 2011 - Elsevier
BACKGROUND:: The symptoms of posttraumatic stress disorder (PTSD) can be explained,
at least in part, as an inability to inhibit learned fear during conditions of safety. Our group
has shown that fear inhibition is impaired in both combat and civilian PTSD populations. On
the basis of our earlier findings, we employed an established fear extinction paradigm to
further explore fear dysregulation in a civilian traumatized population. METHODS:: Fear-
potentiated startle (FPS) was examined in 127 trauma-exposed individuals with and without …
at least in part, as an inability to inhibit learned fear during conditions of safety. Our group
has shown that fear inhibition is impaired in both combat and civilian PTSD populations. On
the basis of our earlier findings, we employed an established fear extinction paradigm to
further explore fear dysregulation in a civilian traumatized population. METHODS:: Fear-
potentiated startle (FPS) was examined in 127 trauma-exposed individuals with and without …