Skin prick test responses and allergen-specific IgE levels as predictors of peanut, egg, and sesame allergy in infants

RL Peters, KJ Allen, SC Dharmage, MLK Tang… - Journal of Allergy and …, 2013 - Elsevier
Background Ninety-five percent positive predictive values (PPVs) provide an invaluable tool
for clinicians to avoid unnecessary oral food challenges. However, 95% PPVs specific to
infants, the age group most likely to present for diagnosis of food allergy, are limited.
Objective We sought to develop skin prick test (SPT) and allergen-specific IgE (sIgE)
thresholds with 95% PPVs for challenge-confirmed food allergy in a large population-based
cohort of 1-year-old infants with challenges undertaken irrespective of SPT wheal size or …