Fall in rectal temperature as an indication of anaphylactic shock in the mouse
LS Kind - The Journal of Immunology, 1955 - journals.aai.org
The Journal of Immunology, 1955•journals.aai.org
A fall in rectal temperature regularly accompanies anaphylactic shock produced by the
intraperitoneal injection of horse serum into horse serum-sensitized mice. The dose of horse
serum which lowered the temperature of sensitized mice did not cause a drop in the
temperature of non-sensitized control animals. Much larger doses of horse serum also had
little effect on the rectal temperature of non-sensitized mice. The advantages to be derived
from the use of thermal measurements in anaphylaxis are discussed.
intraperitoneal injection of horse serum into horse serum-sensitized mice. The dose of horse
serum which lowered the temperature of sensitized mice did not cause a drop in the
temperature of non-sensitized control animals. Much larger doses of horse serum also had
little effect on the rectal temperature of non-sensitized mice. The advantages to be derived
from the use of thermal measurements in anaphylaxis are discussed.
Summary
A fall in rectal temperature regularly accompanies anaphylactic shock produced by the intraperitoneal injection of horse serum into horse serum-sensitized mice. The dose of horse serum which lowered the temperature of sensitized mice did not cause a drop in the temperature of non-sensitized control animals. Much larger doses of horse serum also had little effect on the rectal temperature of non-sensitized mice. The advantages to be derived from the use of thermal measurements in anaphylaxis are discussed.
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