[HTML][HTML] Complement activation in COVID-19 and targeted therapeutic options: a scoping review

EHT Lim, RBE van Amstel, VV de Boer, LA van Vught… - Blood Reviews, 2023 - Elsevier
Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a
systematic approach to create an overview of complement activation in COVID-19 based on
histopathological, preclinical, multiomics, observational and clinical interventional studies. A
total of 1801 articles from PubMed, EMBASE and Cochrane was screened of which 157
articles were included in this scoping review. Histopathological, preclinical, multiomics and …