[HTML][HTML] Differential binding patterns of anti-sulfatide antibodies to glial membranes

GR Meehan, R McGonigal, ME Cunningham… - Journal of …, 2018 - Elsevier
Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in
autoimmune neuropathies. However neuropathy disease models have not been widely
established, in part because currently available monoclonal antibodies to sulfatide may not
represent the diversity of anti-sulfatide antibody binding patterns found in neuropathy
patients. We sought to address this issue by generating and characterising a panel of new
anti-sulfatide monoclonal antibodies. These antibodies have sulfatide reactivity distinct from …