[HTML][HTML] Genetic and neutralization sensitivity of diverse HIV-1 env clones from chronically infected patients in China

H Shang, X Han, X Shi, T Zuo, M Goldin, D Chen… - Journal of Biological …, 2011 - ASBMB
As HIV-1 continues to spread in China from traditional high risk populations to the general
public, its genetic makeup has become increasingly complex. However, the impact of these
genetic changes on the biological and neutralization sensitivity of the virus is unknown. The
current study aims to characterize the genetic, biological, and neutralization sensitivity of HIV-
1 identified in China between 2004 and 2007. Based on a total of 107 full-length envelope
genes obtained directly from the infected patients, we found that those viruses fell into three …