Ulinastatin attenuates lung ischemia-reperfusion injury in rats by inhibiting tumor necrosis factor alpha
B Ren, H Wu, J Zhu, D Li, Y Shen, R Ying… - Transplantation …, 2006 - Elsevier
Ischemia-reperfusion (I/R) injury may influence graft function following transplantation.
Ulinastatin, a urinary trypsin inhibitor has been shown to attenuate I/R injury in various
organs such as intestine, heart, and kidney in animals. The present experiment was
designed to evaluate the effect of pretreatment with ulinastatin on I/R-induced lung injury.
METHODS: After establishing a constant left lung warm ischemia-reperfusion model in rats,
45 animals were randomly divided into three experimental groups: sham group (n= 15), IR …
Ulinastatin, a urinary trypsin inhibitor has been shown to attenuate I/R injury in various
organs such as intestine, heart, and kidney in animals. The present experiment was
designed to evaluate the effect of pretreatment with ulinastatin on I/R-induced lung injury.
METHODS: After establishing a constant left lung warm ischemia-reperfusion model in rats,
45 animals were randomly divided into three experimental groups: sham group (n= 15), IR …
