Standard, immunocompetent, inbred strains of mice are non-permissive for infection with the
human filarial nematode, Brugia malayi or the closely related Brugia pahangi. This non-
permissiveness allows one to address the mechanism (s) that might be used by mammalian
hosts to eliminate large, multicellular, metazoan, extracellular invertebrate pathogens. We
describe here the time course of intraperitoneal Brugian infections in naı̈ve and primed+/+
mice from two commonly used, inbred laboratory strains (C57BL/6J and BALB/cByJ). We …