The expression of CD44v6 in colon: from normal to malignant
A Afify, B Durbin-Johnson, A Virdi, H Jess - Annals of Diagnostic Pathology, 2016 - Elsevier
CD44v6, an integral transmembrane protein belonging to a family of adhesion molecule
receptors, plays an important role in tumor growth, progression and metastasis. The purpose
of this study was to evaluate the expression of CD44v6 in normal, hyperplastic,
adenomatous, and malignant colonic epithelium and to determine its correlation with tumor
pathologic stage and lymph node metastasis. We examined the immunohistochemical
expression of CD44v6 in normal colonic tissue (n= 25), hyperplastic polyps (n= 45), tubular …
receptors, plays an important role in tumor growth, progression and metastasis. The purpose
of this study was to evaluate the expression of CD44v6 in normal, hyperplastic,
adenomatous, and malignant colonic epithelium and to determine its correlation with tumor
pathologic stage and lymph node metastasis. We examined the immunohistochemical
expression of CD44v6 in normal colonic tissue (n= 25), hyperplastic polyps (n= 45), tubular …
