[HTML][HTML] Control of iron metabolism–lessons from neonatal hemochromatosis

H Zoller, AS Knisely - Journal of hepatology, 2012 - journal-of-hepatology.eu
When hepatologists begin their investigations at the scene of liver damage, iron is certainly
on the list of ''usual suspects''to be rounded up. Hemochromatosis, a well-known cause of
chronic liver disease, is the most prevalent genetic disorder in adults [1]. Serum iron
parameters are therefore included in most guidelines on how to investigate patients with
elevated transaminases or chronic liver disease [2]. The hemochromatosis (HFE) genotype
is an important piece of evidence in patients with liver disease and elevated transferrin …