Identification of characteristic IGF2BP expression patterns in distinct B-ALL entities
M Stoskus, E Gineikiene, V Valceckiene… - Blood Cells, Molecules …, 2011 - Elsevier
Insulin-like growth factor 2 mRNA-binding proteins IGF2BP1, IGF2BP2, and IGF2BP3 have
been shown to have diagnostic and prognostic utility in a number of epithelial and soft tissue
tumors. Still, little is known about the expression of these molecules in different types of
leukemia and our study aims to fill this gap. By using an RT–qPCR approach, we have
systemically analyzed the expression of three IGF2BP coding genes in normal
hematopoietic tissues and distinct acute lymphoblastic leukemia (ALL) entities. We show …
been shown to have diagnostic and prognostic utility in a number of epithelial and soft tissue
tumors. Still, little is known about the expression of these molecules in different types of
leukemia and our study aims to fill this gap. By using an RT–qPCR approach, we have
systemically analyzed the expression of three IGF2BP coding genes in normal
hematopoietic tissues and distinct acute lymphoblastic leukemia (ALL) entities. We show …
