Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
BACKGROUND/AIMS: To characterize IL-17-producing cells, a newly defined T helper cell
subset with potent pro-inflammatory properties, in hepatocellular carcinoma (HCC) and to
determine their prognostic values. METHODS: One hundred and seventy-eight HCC
patients were enrolled randomly. Distribution and phenotypic features of IL-17-producing
cells were determined by flow cytometry and/or immunohistochemistry. RESULTS:
Compared with corresponding non-tumor regions, the levels of Th17 cells were significantly …
subset with potent pro-inflammatory properties, in hepatocellular carcinoma (HCC) and to
determine their prognostic values. METHODS: One hundred and seventy-eight HCC
patients were enrolled randomly. Distribution and phenotypic features of IL-17-producing
cells were determined by flow cytometry and/or immunohistochemistry. RESULTS:
Compared with corresponding non-tumor regions, the levels of Th17 cells were significantly …