[CITATION][C] To metastasize or not? Selection of CD44 splice sites
DL Cooper, GJ Dougherty - Nature medicine, 1995 - nature.com
DL Cooper, GJ Dougherty
Nature medicine, 1995•nature.com, , , , , , NEWS S VIEWS Page 1 TG) 1995 Nature Publishing Group http://www.nature.com/naturemedicine
, , , , , , NEWS S VIEWS Following the initial demonstration by Gunthert et al." that a variant of
the widely distributed cell surface adhesion protein CD44 could confer metastatic potential
on a rat pancreatic adenocarcinoma cell line, a great deal of scientific interest has focused
on attempting to better define the role that this unique molecule may play in tumour growth
and metastasis. In the last 5 years, close to 100 papers dealing directly with this sometimes …
, , , , , , NEWS S VIEWS Following the initial demonstration by Gunthert et al." that a variant of
the widely distributed cell surface adhesion protein CD44 could confer metastatic potential
on a rat pancreatic adenocarcinoma cell line, a great deal of scientific interest has focused
on attempting to better define the role that this unique molecule may play in tumour growth
and metastasis. In the last 5 years, close to 100 papers dealing directly with this sometimes …
The role of the CD44 cell surface molecule in tumorigenesis has been the focus of intense debate. Now enough pieces are known to begin putting the puzzle together.
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