Migration of dendritic cells into lymphatics—the Langerhans cell example: routes, regulation, and relevance
N Romani, G Ratzinger, K Pfaller… - International review of …, 2001 - Elsevier
Dendritic cells are leukocytes of bone marrow origin. They are central to the control of the
immune response. Dendritic cells are highly specialized in processing and presenting
antigens (microbes, proteins) to helper T lymphocytes. Thereby, they critically regulate
further downstream processes such as the development of cytotoxic T lymphocytes, the
production of antibodies by B lymphocytes, or the activation of macrophages. A new field of
dendritic cell biology is the study of their potential role in inducing peripheral tolerance. The …
immune response. Dendritic cells are highly specialized in processing and presenting
antigens (microbes, proteins) to helper T lymphocytes. Thereby, they critically regulate
further downstream processes such as the development of cytotoxic T lymphocytes, the
production of antibodies by B lymphocytes, or the activation of macrophages. A new field of
dendritic cell biology is the study of their potential role in inducing peripheral tolerance. The …
